Sign Out
INSTRUCTIONS FOR USE: BREZTRI AEROSPHERE (budesonide, glycopyrronium, and formoterol fumarate dihydrate): Pressurised inhalation, suspension.
For oral inhalation use.
Your Breztri Aerosphere (called "inhaler" in this monograph) may be different from inhalers you have used before.
Important information: For oral inhalation use only.
Prepare your inhaler for its first time use by priming it.
Rinse your yellow actuator weekly.
Take 2 puffs of medicine in the morning and 2 puffs of medicine in the evening.
Storing your inhaler: Store your inhaler below 30°C.
Do not store in a humid environment, such as a bathroom.
Keep your inhaler and all medicines out of the reach of children.
Parts of your inhaler: Puff indicator: Attached to the top of the pressurised canister.
Pressurised Canister (inside): Holds the medicine.
Actuator: Contains the pressurised canister.
Mouthpiece: Sprays the medicine.
Mouthpiece cover: Protects the mouthpiece when the inhaler is not in use.
Reading the puff indicator: The puff indicator will count down by 1 each time you spray a puff of medicine.
Pointer: Points to number of puffs remaining.
Yellow zone: Order a new inhaler when the pointer is in the yellow zone.
Red zone: Throw away your inhaler when the pointer is at 0 in the red zone.
The display window for the 30-day inhaler shows 120.
Do not try to take a puff when the pointer is at 0 because you will not receive a full dose.
Ordering a new inhaler: Order a new inhaler when the pointer on the puff indicator is in the yellow zone.
Throwing away your inhaler: Throw away your inhaler following local guidelines when: puff indicator shows 0; or 3 months (for the 30-day inhaler) after your inhaler has been removed from the foil pouch.
Do not reuse or use the actuator with medicine canisters from other inhalers.
Do not puncture or throw the canister into a fire or incinerator.
BEFORE FIRST USE - Prime your inhaler 4 times before first use: Before you use your inhaler for the first time, prime it so that you will get the right amount of medicine when you use it.
Prime 1: Remove mouthpiece cover.
Prime 2: Shake the inhaler well and spray 1 Test-puff into the air facing away from you. Repeat for a total of 4 Test-puffs, shaking before each Test-puff.
Extra puffs are provided for priming. Do not skip priming.
Re-prime your inhaler: after rinsing the actuator; if dropped; if not used for more than 7 days.
To re-prime, spray 2 Test-puffs, shaking before each Test-puff.
DAILY USE, morning & evening - Inhale your medicine: Daily Dose: 2 puffs in the morning and 2 puffs in the evening.
Rinse mouth with water after the 2 puffs to prevent fungal infection.
Step 1: Remove mouthpiece cover. Check the mouthpiece for foreign objects and remove objects before use.
Step 2: Shake the inhaler well before each puff.
Breathe out fully.
Place mouthpiece into mouth and close lips around the mouthpiece.
Start to breathe in deeply and slowly while spraying 1 puff. Continue breathing in until you cannot any more.
Hold breath for as long as you can, up to 10 seconds.
Step 3: Repeat Step 2 for a second puff.
Step 4: Put mouthpiece cover back on.
Step 5: Rinse mouth with water. Spit out water. Do not swallow.
WEEKLY RINSE - Rinse your actuator once a week: Rinse yellow actuator weekly so that medicine does not build up and block the spray through the mouthpiece.
Do not allow the canister to get wet.
Re-prime after rinsing.
Rinse 1: Remove canister and set aside. Do not allow the canister to get wet.
Rinse 2: Remove mouthpiece cover.
Rinse 3: Run warm water through the mouthpiece for 30 seconds and then through the top of the actuator for 30 seconds. Rinse for 60 seconds in total.
Rinse 4: Shake off as much water as you can.
Do not dry with a towel or tissue.
Rinse 5: Look into the actuator and mouthpiece for medicine build-up. If there is any build-up, repeat steps Rinse 3 through 5.
Rinse 6: Air-dry, preferably overnight. Do not put the canister back into the actuator if it is still wet.
Rinse 7: When dry, replace the mouthpiece cover first and then gently press the canister down into the actuator.
Rinse 8: Re-prime the inhaler by spraying 2 Test-puffs, shaking before each Test-puff.
